Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma

The angiotensin-(1–7) [Ang-(1–7)]/MAS1 receptor signaling axis is a key endogenous anti-inflammatory signaling pathway. However, the mechanisms by which its mediates the anti-inflammatory effects are not completely understood. Using an allergic murine model of asthma, we investigated whether Ang-1(1...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: El-Hashim, Ahmed Z., Khajah, Maitham A., Babyson, Rhema S., Renno, Waleed M., Ezeamuzie, Charles I., Benter, Ibrahim F., Akhtar, Saghir
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824568/
https://ncbi.nlm.nih.gov/pubmed/31675376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224163
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires