Angiotensin-(1–7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways

BACKGROUND AND PURPOSE: Angiotensin-(1–7) [Ang-(1–7)] has anti-inflammatory effects in models of cardiovascular disease and arthritis, but its effects in asthma are unknown. We investigated whether Ang-(1–7) has anti-inflammatory actions in a murine model of asthma. EXPERIMENTAL APPROACH: The effect...

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Detalhes bibliográficos
Main Authors: El-Hashim, Ahmed Z, Renno, Waleed M, Raghupathy, Raj, Abduo, Heba T, Akhtar, Saghir, Benter, Ibrahim F
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402818/
https://ncbi.nlm.nih.gov/pubmed/22339213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01905.x
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