Antifibrotic effect of Ac-SDKP and angiotensin-converting enzyme inhibition in hypertension

OBJECTIVE: N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is a potent natural inhibitor of hematopoietic stem cell proliferation which is degraded mainly by angiotensin-converting enzyme (ACE). In vitro, Ac-SDKP inhibits collagen production by cardiac fibroblasts; while in vivo it blocks collagen d...

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Detalhes bibliográficos
Publicado no:J Hypertens
Main Authors: Rasoul, Saman, Carretero, Oscar A., Peng, Hongmei, Cavasin, Maria A., Zhuo, Jialong, Sanchez-Mendoza, Alicia, Brigstock, David R., Rhaleb, Nour-Eddine
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824438/
https://ncbi.nlm.nih.gov/pubmed/15076166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/00004872-200403000-00023
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