Characterization and localization of Ac-SDKP receptor binding sites using (125)I-labeled Hpp-Aca-SDKP in rat cardiac fibroblasts

We have shown that the tetrapeptide N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) inhibited endothelin-1 (ET-1)-induced cell proliferation and collagen synthesis in cultured rat cardiac fibroblasts (CFs) and reduced left ventricle collagen deposition in rats with aldosterone (salt)- and ANG II-ind...

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Главные авторы: Zhuo, Jia L., Carretero, Oscar A., Peng, Hongmei, Li, Xiao C., Regoli, Domenico, Neugebauer, Witold, Rhaleb, Nour-Eddine
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276842/
https://ncbi.nlm.nih.gov/pubmed/17028162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00776.2006
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