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Characterization and localization of Ac-SDKP receptor binding sites using (125)I-labeled Hpp-Aca-SDKP in rat cardiac fibroblasts
We have shown that the tetrapeptide N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) inhibited endothelin-1 (ET-1)-induced cell proliferation and collagen synthesis in cultured rat cardiac fibroblasts (CFs) and reduced left ventricle collagen deposition in rats with aldosterone (salt)- and ANG II-ind...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276842/ https://ncbi.nlm.nih.gov/pubmed/17028162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00776.2006 |
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