Long Chain Lipid Hydroperoxides Increase the Glutathione Redox Potential Through Glutathione Peroxidase 4

BACKGROUND: Peroxidation of PUFAs by a variety of endogenous and xenobiotic electrophiles is a recognized pathophysiological process that can lead to adverse health effects. Although secondary products generated from peroxidized PUFAs have been relatively well studied, the role of primary lipid hydr...

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Veröffentlicht in:Biochim Biophys Acta Gen Subj
Hauptverfasser: Corteselli, Elizabeth M., Gibbs-Flournoy, Eugene, Simmons, Steven O., Bromberg, Philip, Gold, Avram, Samet, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823641/
https://ncbi.nlm.nih.gov/pubmed/30844486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2019.03.002
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