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Covalent Heterobivalent Inhibitor Design for Inhibition of IgE Dependent Penicillin Allergy in a Murine Model
Drug allergies occur when hapten-like drug metabolites conjugated to serum proteins, through their interactions with specific immunoglobulin E (IgE), trigger allergic reactions that can be life-threatening. A molecule termed covalent heterobivalent inhibitor (cHBI) was designed to specifically targe...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6823631/ https://ncbi.nlm.nih.gov/pubmed/31101666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900225 |
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