Inflammasome Activation Induced by Perfringolysin O of Clostridium perfringens and Its Involvement in the Progression of Gas Gangrene

Clostridium perfringens (C. perfringens) is Gram-positive anaerobic, spore-forming rod-shaped bacterial pathogen that is widely distributed in nature. This bacterium is known as the causative agent of a foodborne illness and of gas gangrene. While the major virulence factors are the α-toxin and perf...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Yamamura, Kiyonobu, Ashida, Hiroshi, Okano, Tokuju, Kinoshita-Daitoku, Ryo, Suzuki, Shiho, Ohtani, Kaori, Hamagaki, Miwako, Ikeda, Tohru, Suzuki, Toshihiko
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823607/
https://ncbi.nlm.nih.gov/pubmed/31708887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02406
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