Inhibition of HDAC4 Attenuated JNK/c-Jun-Dependent Neuronal Apoptosis and Early Brain Injury Following Subarachnoid Hemorrhage by Transcriptionally Suppressing MKK7

The c-Jun N-terminal kinase (JNK)/c-Jun cascade-dependent neuronal apoptosis has been identified as a central element for early brain injury (EBI) following subarachnoid hemorrhage (SAH), but the molecular mechanisms underlying this process are still thoroughly undefined to date. In this study, we f...

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Publicat a:Front Cell Neurosci
Autors principals: Wu, Liqiang, Zeng, Shulian, Cao, Yali, Huang, Ziyan, Liu, Sisi, Peng, Huaidong, Zhi, Cheng, Ma, Shanshan, Hu, Kunhua, Yuan, Zhongmin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Cellular Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823346/
https://ncbi.nlm.nih.gov/pubmed/31708743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00468
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