Loss of Antigen Presentation in Adipose Tissue Macrophages or in Adipocytes, but not Both, Improves Glucose Metabolism()

Macrophages, B cells and adipocytes are among the adipose tissue (AT) antigen presenting cells (APCs) that differentiate and activate naïve CD4+ T cells. Mice with adipocyte loss of major histocompatibility complex II (MHCII) are more insulin sensitive. Since macrophages are professional APCs, mice...

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Publicado en:J Immunol
Main Authors: Blaszczak, Alecia M, Wright, Valerie P, Anandani, Kajol, Liu, Joey, Jalilvand, Anahita, Bergin, Stephen, Nicoloro, Sarah M, Czech, Michael P, Lafuse, William, Deng, Tuo, Bradley, David, Hsueh, Willa A
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822681/
https://ncbi.nlm.nih.gov/pubmed/30850480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801470
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