Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads

As metagenomic studies move to increasing numbers of samples, communities like the human gut may benefit more from the assembly of abundant microbes in many samples, rather than the exhaustive assembly of fewer samples. We term this approach leaderboard metagenome sequencing. To explore protocol opt...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Sanders, Jon G., Nurk, Sergey, Salido, Rodolfo A., Minich, Jeremiah, Xu, Zhenjiang Z., Zhu, Qiyun, Martino, Cameron, Fedarko, Marcus, Arthur, Timothy D., Chen, Feng, Boland, Brigid S., Humphrey, Greg C., Brennan, Caitriona, Sanders, Karenina, Gaffney, James, Jepsen, Kristen, Khosroheidari, Mahdieh, Green, Cliff, Liyanage, Marlon, Dang, Jason W., Phelan, Vanessa V., Quinn, Robert A., Bankevich, Anton, Chang, John T., Rana, Tariq M., Conrad, Douglas J., Sandborn, William J., Smarr, Larry, Dorrestein, Pieter C., Pevzner, Pavel A., Knight, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822431/
https://ncbi.nlm.nih.gov/pubmed/31672156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1834-9
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