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T cells promote microglia-mediated synaptic elimination and cognitive dysfunction during recovery from neuropathogenic flaviviruses

T cells clear virus from the CNS and dynamically regulate brain functions, including spatial learning, through cytokine signaling. Here we determined whether hippocampal T cells that persist after recovery from infection with West Nile virus (WNV) or Zika virus (ZIKV) impact hippocampal-dependent le...

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書目詳細資料
發表在:Nat Neurosci
Main Authors: Garber, Charise, Soung, Allison, Vollmer, Lauren L., Kanmogne, Marlene, Last, Aisling, Brown, Jasmine, Klein, Robyn S.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822175/
https://ncbi.nlm.nih.gov/pubmed/31235930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0427-y
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