Long-term dabigatran treatment delays Alzheimer’s disease pathogenesis in the TgCRND8 mouse model

BACKGROUND –: Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder with important vascular and hemostatic alterations that should be taken into account during diagnosis and treatment. OBJECTIVES –: This study evaluates whether anticoagulation with dabigatran, a clinically approved...

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Detalhes bibliográficos
Publicado no:J Am Coll Cardiol
Main Authors: Cortes-Canteli, Marta, Kruyer, Anna, Fernandez-Nueda, Irene, Marcos-Diaz, Ana, Ceron, Carlos, Richards, Allison T., Jno-Charles, Odella C., Rodriguez, Ignacio, Callejas, Sergio, Norris, Erin H., Sanchez-Gonzalez, Javier, Ruiz-Cabello, Jesus, Ibanez, Borja, Strickland, Sidney, Fuster, Valentin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822166/
https://ncbi.nlm.nih.gov/pubmed/31601371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.07.081
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