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mTORC1 and CB1 receptor signaling regulate excitatory glutamatergic inputs onto the hypothalamic paraventricular nucleus in response to energy availability

OBJECTIVE: The hypothalamic paraventricular nucleus (PVN) is a key target of the melanocortin system, which orchestrates behavioral and metabolic responses depending on energy availability. The mechanistic target of rapamycin complex 1 (mTORC1) and the endocannabinoid type 1 receptor (CB1R) pathways...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Mazier, Wilfrid, Saucisse, Nicolas, Simon, Vincent, Cannich, Astrid, Marsicano, Giovanni, Massa, Federico, Cota, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822143/
https://ncbi.nlm.nih.gov/pubmed/31420305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.08.005
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