IMP-68, a Novel IMP-Type Metallo-β-Lactamase in Imipenem-Susceptible Klebsiella pneumoniae

We recently detected a novel variant of an IMP-type metallo-β-lactamase gene (bla(IMP-68)) from meropenem-resistant but imipenem-susceptible Klebsiella pneumoniae TA6363 isolated in Tokyo, Japan. bla(IMP-68) encodes a Ser262Gly point mutant of IMP-11, and transformation experiments showed that bla(I...

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Publicado en:mSphere
Autores principales: Kubota, Hiroaki, Suzuki, Yasunori, Okuno, Rumi, Uchitani, Yumi, Ariyoshi, Tsukasa, Takemura, Nobuyuki, Mihara, Fuminori, Mezaki, Kazuhisa, Ohmagari, Norio, Matsui, Mari, Suzuki, Satowa, Sekizuka, Tsuyoshi, Kuroda, Makoto, Yokoyama, Keiko, Sadamasu, Kenji
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2019
Materias:
Observation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821933/
https://ncbi.nlm.nih.gov/pubmed/31666316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00736-19
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