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The plasmid-encoded transcription factor ArdK contributes to the repression of the IMP-6 metallo-β-lactamase gene bla(IMP-6), leading to a carbapenem-susceptible phenotype in the bla(IMP-6)-positive Escherichia coli strain A56-1S

Carbapenemase-producing Enterobacteriaceae (CPE) are a global concern because these bacteria are resistant to almost all β-lactams. Horizontal interspecies gene transfer via plasmid conjugation has increased the global dissemination of CPE. Recently, an Enterobacteriaceae strain positive for carbape...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Segawa, Takaya, Sekizuka, Tsuyoshi, Suzuki, Satowa, Shibayama, Keigo, Matsui, Mari, Kuroda, Makoto
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289460/
https://ncbi.nlm.nih.gov/pubmed/30533034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208976
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