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The neuronal ceroid lipofuscinosis protein Cln7 functions in the postsynaptic cell to regulate synapse development

The neuronal ceroid lipofuscinoses (NCLs) are a group of fatal, monogenic neurodegenerative disorders with an early onset in infancy or childhood. Despite identification of the genes disrupted in each form of the disease, their normal cellular role and how their deficits lead to disease pathology is...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Connolly, Kyle J., O’Hare, Megan B., Mohammed, Alamin, Aitchison, Katelyn M., Anthoney, Niki C., Taylor, Matthew J., Stewart, Bryan A., Tuxworth, Richard I., Tear, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821864/
https://ncbi.nlm.nih.gov/pubmed/31666534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51588-w
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