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The neuronal ceroid lipofuscinosis protein Cln7 functions in the postsynaptic cell to regulate synapse development

The neuronal ceroid lipofuscinoses (NCLs) are a group of fatal, monogenic neurodegenerative disorders with an early onset in infancy or childhood. Despite identification of the genes disrupted in each form of the disease, their normal cellular role and how their deficits lead to disease pathology is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Connolly, Kyle J., O’Hare, Megan B., Mohammed, Alamin, Aitchison, Katelyn M., Anthoney, Niki C., Taylor, Matthew J., Stewart, Bryan A., Tuxworth, Richard I., Tear, Guy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821864/
https://ncbi.nlm.nih.gov/pubmed/31666534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51588-w
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