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Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex

DNA gyrase is an essential enzyme involved in the homeostatic control of DNA supercoiling and the target of successful antibacterial compounds. Despite extensive studies, a detailed architecture of the full-length DNA gyrase from the model organism E. coli is still missing. Herein, we report the com...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Vanden Broeck, Arnaud, Lotz, Christophe, Ortiz, Julio, Lamour, Valérie
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821735/
https://ncbi.nlm.nih.gov/pubmed/31666516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12914-y
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