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An Open-label Extension Study of Ivacaftor in Children With CF and a CFTR Gating Mutation Initiating Treatment at Age 2-5 Years (KLIMB)
BACKGROUND: KIWI (NCT01705145) was a 24-week, single-arm, pharmacokinetics, safety, and efficacy study of ivacaftor in children aged 2 to 5 years with cystic fibrosis (CF) and a CFTR gating mutation. Here, we report the results of KLIMB (NCT01946412), an 84-week, open-label extension of KIWI. METHOD...
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Publicat a: | J Cyst Fibros |
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Autors principals: | , , , , , , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2019
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6821553/ https://ncbi.nlm.nih.gov/pubmed/31053538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2019.03.009 |
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