Human Trophoblast Differentiation Is Associated With Profound Gene Regulatory and Epigenetic Changes

Defective placental implantation and vascularization with accompanying hypoxia contribute to preeclampsia (PE), a leading cause of maternal and neonatal morbidity and mortality. Genetic and epigenetic mechanisms underlying differentiation of proliferative cytotrophoblasts (CytTs) to multinucleated s...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Kwak, Youn-Tae, Muralimanoharan, Sribalasubashini, Gogate, Aishwarya A, Mendelson, Carole R
Format: Artigo
Language:Inglês
Published: Endocrine Society 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821221/
https://ncbi.nlm.nih.gov/pubmed/31294776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2019-00144
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