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Redox-Sensitive Transcription Factor NRF2 Enhances Trophoblast Differentiation via Induction of miR-1246 and Aromatase

Dysregulation of human trophoblast invasion and differentiation with placental hypoxia can result in preeclampsia, a hypertensive disorder of pregnancy. Herein, we characterized the role and regulation of miR-1246, which is markedly induced during human syncytiotrophoblast differentiation. miR-1246...

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Publicado en:Endocrinology
Main Authors: Muralimanoharan, Sribalasubashini, Kwak, Youn-Tae, Mendelson, Carole R
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5905392/
https://ncbi.nlm.nih.gov/pubmed/29546425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-03024
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