Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration

Over the past decade, the transactive response DNA-binding protein of 43 kDa (TDP-43) has been recognized as a major protein in normal and pathological ageing, increasing the risk of cognitive impairment and dementia. In conditions distinct from the frontotemporal lobar degenerations, TDP-43 appears...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Bejanin, Alexandre, Murray, Melissa E, Martin, Peter, Botha, Hugo, Tosakulwong, Nirubol, Schwarz, Christopher G, Senjem, Matthew L, Chételat, Gael, Kantarci, Kejal, Jack, Clifford R, Boeve, Bradley F, Knopman, David S, Petersen, Ronald C, Giannini, Caterina, Parisi, Joseph E, Dickson, Dennis W, Whitwell, Jennifer L, Josephs, Keith A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821218/
https://ncbi.nlm.nih.gov/pubmed/31562527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz277
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