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TPES: tumor purity estimation from SNVs

MOTIVATION: Tumor purity (TP) is the proportion of cancer cells in a tumor sample. TP impacts on the accurate assessment of molecular and genomics features as assayed with NGS approaches. State-of-the-art tools mainly rely on somatic copy-number alterations (SCNA) to quantify TP and therefore fail w...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Locallo, Alessio, Prandi, Davide, Fedrizzi, Tarcisio, Demichelis, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821153/
https://ncbi.nlm.nih.gov/pubmed/31099386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz406
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