Leucine-rich diet induces a shift in tumour metabolism from glycolytic towards oxidative phosphorylation, reducing glucose consumption and metastasis in Walker-256 tumour-bearing rats

Leucine can stimulate protein synthesis in skeletal muscle, and recent studies have shown an increase in leucine-related mitochondrial biogenesis and oxidative phosphorylation capacity in muscle cells. However, leucine-related effects in tumour tissues are still poorly understood. Thus, we described...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Viana, Laís Rosa, Tobar, Natália, Busanello, Estela Natacha Brandt, Marques, Ana Carolina, de Oliveira, Andre Gustavo, Lima, Tanes I., Machado, Gabrielly, Castelucci, Bianca Gazieri, Ramos, Celso Dario, Brunetto, Sérgio Q, Silveira, Leonardo Reis, Vercesi, Anibal Eugenio, Consonni, Sílvio Roberto, Gomes-Marcondes, Maria Cristina Cintra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820796/
https://ncbi.nlm.nih.gov/pubmed/31664147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52112-w
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