Amyloid-Beta Modulates Low-Threshold Activated Voltage-Gated L-Type Calcium Channels of Arcuate Neuropeptide Y Neurons Leading to Calcium Dysregulation and Hypothalamic Dysfunction

Weight loss is an early manifestation of Alzheimer's disease that can precede the cognitive decline, raising the possibility that amyloid-β (Aβ) disrupts hypothalamic neurons critical for the regulation of body weight. We previously reported that, in young transgenic mice overexpressing mutated...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Ishii, Makoto, Hiller, Abigail J., Pham, Laurie, McGuire, Matthew J., Iadecola, Costantino, Wang, Gang
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820205/
https://ncbi.nlm.nih.gov/pubmed/31537707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0617-19.2019
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky