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Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease

IMPORTANCE: Corticolimbic patterns of neurofibrillary tangle (NFT) accumulation define neuropathologic subtypes of Alzheimer disease (AD), which underlie the clinical heterogeneity observed antemortem. The cholinergic system, which is the target of acetylcholinesterase inhibitor therapy, is selectiv...

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Detaylı Bibliyografya
Yayımlandı:JAMA Neurol
Asıl Yazarlar: Hanna Al-Shaikh, Fadi S., Duara, Ranjan, Crook, Julia E., Lesser, Elizabeth R., Schaeverbeke, Jolien, Hinkle, Kelly M., Ross, Owen A., Ertekin-Taner, Nilufer, Pedraza, Otto, Dickson, Dennis W., Graff-Radford, Neill R., Murray, Melissa E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Medical Association 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820048/
https://ncbi.nlm.nih.gov/pubmed/31657834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.3606
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