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Extracellular binding of indinavir to matrix metalloproteinase-2 and the alpha-7-nicotinic acetylcholine receptor: implications for use in cancer treatment

INTRODUCTION: Results from recent studies have suggested a role for protease inhibitors in altering mechanisms involved in the initiation and proliferation of cancer cells. One such inhibitor, indinavir, may act as an anti-cancer agent by modulating the alpha-7-nicotinic acetylcholine receptor, whic...

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Detalles Bibliográficos
Publicado en:Heliyon
Main Authors: Lee, Anna, Saito, Erin, Ekins, Sean, McMurtray, Aaron
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819839/
https://ncbi.nlm.nih.gov/pubmed/31687607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2019.e02526
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