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Nrf2 signaling links ER oxidative protein folding and calcium homeostasis in health and disease
We report a signaling pathway linking two fundamental functions of the ER, oxidative protein folding, and intracellular calcium regulation. Cells sense ER oxidative protein folding through H(2)O(2,) which induces Nrf2 nuclear translocation. Nrf2 regulates the expression of GPx8, an ER glutathione pe...
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| Publicado no: | Life Sci Alliance |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6819749/ https://ncbi.nlm.nih.gov/pubmed/31658977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900563 |
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