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Dipeptidyl-peptidase-4 (DPP-4) inhibitor ameliorates 5-flurouracil induced intestinal mucositis

BACKGROUND: Chemotherapy-induced alimentary mucositis (AM) is difficult to prevent and treatment is rarely effective. Recent study have been showed that glucagon-like peptide (GLP)-1 and GLP-2 has protective in chemotherapy-induced AM. While the DPP-4 enzyme degrades this GLP-1, the DPP-4 inhibitor...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Lee, Jung Min, Yoo, In Kyung, Lee, Jae Min, Kim, Seung Han, Choi, Hyuk Soon, Kim, Eun Sun, Keum, Bora, Seo, Yeon Seok, Jeen, Yoon Tae, Chun, Hoon Jai, Lee, Hong Sik, Um, Soon Ho, Kim, Chang Duck
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819400/
https://ncbi.nlm.nih.gov/pubmed/31664952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6231-y
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