Dipeptidyl-peptidase-4 (DPP-4) inhibitor ameliorates 5-flurouracil induced intestinal mucositis

BACKGROUND: Chemotherapy-induced alimentary mucositis (AM) is difficult to prevent and treatment is rarely effective. Recent study have been showed that glucagon-like peptide (GLP)-1 and GLP-2 has protective in chemotherapy-induced AM. While the DPP-4 enzyme degrades this GLP-1, the DPP-4 inhibitor...

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Опубликовано в: :BMC Cancer
Главные авторы: Lee, Jung Min, Yoo, In Kyung, Lee, Jae Min, Kim, Seung Han, Choi, Hyuk Soon, Kim, Eun Sun, Keum, Bora, Seo, Yeon Seok, Jeen, Yoon Tae, Chun, Hoon Jai, Lee, Hong Sik, Um, Soon Ho, Kim, Chang Duck
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819400/
https://ncbi.nlm.nih.gov/pubmed/31664952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6231-y
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