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Exchange Saturation Transfer and Associated NMR Techniques for Studies of Protein Interactions Involving High-Molecular-Weight Systems

A brief overview of theoretical and experimental aspects of the Dark state Exchange Saturation Transfer (DEST) and lifetime line broadening (ΔR(2)) NMR methodologies is presented from a physico-chemical perspective. We describe how the field-dependence of ΔR(2) can be used for determining the exchan...

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Detalhes bibliográficos
Publicado no:J Biomol NMR
Main Authors: Tugarinov, Vitali, Clore, G. Marius
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819251/
https://ncbi.nlm.nih.gov/pubmed/31407202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-019-00244-6
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