HIPPO SIGNALING CONTROLS NLRP3 ACTIVATION AND GOVERNS IMMUNOREGULATION OF MESENCHYMAL STEM CELLS IN MOUSE LIVER INJURY

The Hippo pathway, an evolutionarily conserved protein kinase cascade, tightly regulates cell growth and survival. Activation of yes-associated protein (YAP), a downstream effector of the Hippo pathway, has been shown to modulate tissue inflammation. However, it remains unknown as to whether and how...

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Pubblicato in:Hepatology
Autori principali: Li, Changyong, Jin, Yuting, Wei, Song, Sun, Yishuang, Jiang, Longfeng, Zhu, Qiang, Farmer, Douglas G., Busuttil, Ronald W., Kupiec-Weglinski, Jerzy W., Ke, Bibo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819196/
https://ncbi.nlm.nih.gov/pubmed/31063235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30700
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