The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP

Lysosomes are major sites for intracellular, acidic hydrolase-mediated proteolysis and cellular degradation. The export of low-molecular-weight catabolic end-products is facilitated by polytopic transmembrane proteins mediating secondary active or passive transport. A number of these lysosomal trans...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Massa López, David, Thelen, Melanie, Stahl, Felix, Thiel, Christian, Linhorst, Arne, Sylvester, Marc, Hermanns-Borgmeyer, Irm, Lüllmann-Rauch, Renate, Eskild, Winnie, Saftig, Paul, Damme, Markus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2019
Gaiak:
Biochemistry and Chemical Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819133/
https://ncbi.nlm.nih.gov/pubmed/31661432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50025
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