Involvement of phosphatase and tensin homolog-induced putative kinase 1–Parkin-mediated mitophagy in septic acute kidney injury

BACKGROUND: Studies have reported mitophagy activation in renal tubular epithelial cells (RTECs) in acute kidney injury (AKI). Phosphatase and tensin homolog-induced putative kinase 1 (PINK1) and E3 ubiquitin-protein ligase Parkin are involved in mitophagy regulation; however, little is known about...

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Опубликовано в: :Chin Med J (Engl)
Главные авторы: Dai, Xin-Gui, Xu, Wei, Li, Tao, Lu, Jia-Ying, Yang, Yang, Li, Qiong, Zeng, Zhen-Hua, Ai, Yu-Hang
Формат: Artigo
Язык:Inglês
Опубликовано: Wolters Kluwer Health 2019
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6819035/
https://ncbi.nlm.nih.gov/pubmed/31567378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CM9.0000000000000448
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