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Short-chain Fatty Acids, 4-phenylbutyric Acid and R-α-lipoic Acid, Downregulate mTORC1-dependent Intestinal Fat Absorption (P08-115-19)

OBJECTIVES: Knowing that (i) high-fat diets upregulate inflammatory biomarkers in the small intestine and activate the mechanistic target of rapamycin complex 1 (mTORC1, a conserved protein kinase) and (ii) mTORC1 drives hepatic VLDL secretion, we investigated the role of intestinal mTORC1 in fat ab...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Moreau, Regis, He, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818897/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzz044.P08-115-19
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