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Endocrine Hormone Beta-estradiol and Anti-estrogen Letrozole Modulate 20:3 Isomer Production from 20:2n-6 in Human Cancer Cells (P08-119-19)
OBJECTIVES: The product of linoleic acid elongation, 20:2n-6, is the only known substrate for both FADS1 and FADS2. FADS1 catalyzes 20:2n-6 à 5Z,11Z,14Z-20:3 (sciadonic acid, SA), whereas FADS2 action yields 8Z,11Z,14Z-20:3 (DGLA). In certain cancer cell types, non-functional FADS2 activity unmasks...
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| 出版年: | Curr Dev Nutr |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6818866/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzz044.P08-119-19 |
| タグ: |
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