Metabolic regulation of gene expression by histone lactylation

The Warburg effect, originally describing augmented lactogenesis in cancer, is associated with diverse cellular processes such as angiogenesis, hypoxia, macrophage polarization, and T-cell activation. This phenomenon is intimately linked with multiple diseases including neoplasia, sepsis, and autoim...

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Udgivet i:Nature
Main Authors: Zhang, Di, Tang, Zhanyun, Huang, He, Zhou, Guolin, Cui, Chang, Weng, Yejing, Liu, Wenchao, Kim, Sunjoo, Lee, Sangkyu, Perez-Neut, Mathew, Czyz, Daniel, Hu, Rong, Ye, Zhen, He, Maomao, Zheng, Y. George, Shuman, Howard, Ding, Jun, Dai, Lunzhi, Ren, Bing, Roeder, Robert G., Becker, Lev, Zhao, Yingming
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818755/
https://ncbi.nlm.nih.gov/pubmed/31645732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1678-1
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