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Gene mutation and pedigree analysis of tetrahydrobiopterin deficiency in a Uygur family of China

BACKGROUND: Tetrahydrobiopterin (BH (4)) deficiency is an autosomal recessive disorder, which is caused by an enzyme deficiency involved in its synthetic or metabolic pathways. Clinical symptoms may include microcephaly, hypoevolutism, severe ataxia, and seizures. The purposes of this study are to a...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Li, Long, Qin, Yulan, Su, Yajie, Jiang, Haili, Rejiafu, Nuerya, Li, Mingzhu, Muhetaer, Ayijiamali, Liu, Yongqiao, Ren, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818561/
https://ncbi.nlm.nih.gov/pubmed/30221392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22665
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