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Autophagy induction by tetrahydrobiopterin deficiency

Tetrahydrobiopterin (BH(4)) deficiency is a genetic disorder associated with a variety of metabolic syndromes such as phenylketonuria (PKU). In this article, the signaling pathway by which BH(4) deficiency inactivates mTORC1 leading to the activation of the autophagic pathway was studied utilizing B...

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Autors principals: Kwak, Sang Su, Suk, Jinkyu, Choi, Ji Hye, Yang, Seungkyung, Kim, Jin Woo, Sohn, Seonghyang, Chung, Jae Hoon, Hong, Yong Hee, Lee, Dong Hwan, Ahn, Jeong Keun, Min, Hyesun, Fu, Ya-Min, Meadows, Gary G, Joe, Cheol O
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242797/
https://ncbi.nlm.nih.gov/pubmed/21795851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.11.16627
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