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Autophagy induction by tetrahydrobiopterin deficiency
Tetrahydrobiopterin (BH(4)) deficiency is a genetic disorder associated with a variety of metabolic syndromes such as phenylketonuria (PKU). In this article, the signaling pathway by which BH(4) deficiency inactivates mTORC1 leading to the activation of the autophagic pathway was studied utilizing B...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242797/ https://ncbi.nlm.nih.gov/pubmed/21795851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.11.16627 |
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