Autophagy induction by tetrahydrobiopterin deficiency

Tetrahydrobiopterin (BH(4)) deficiency is a genetic disorder associated with a variety of metabolic syndromes such as phenylketonuria (PKU). In this article, the signaling pathway by which BH(4) deficiency inactivates mTORC1 leading to the activation of the autophagic pathway was studied utilizing B...

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Detalhes bibliográficos
Main Authors: Kwak, Sang Su, Suk, Jinkyu, Choi, Ji Hye, Yang, Seungkyung, Kim, Jin Woo, Sohn, Seonghyang, Chung, Jae Hoon, Hong, Yong Hee, Lee, Dong Hwan, Ahn, Jeong Keun, Min, Hyesun, Fu, Ya-Min, Meadows, Gary G, Joe, Cheol O
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242797/
https://ncbi.nlm.nih.gov/pubmed/21795851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.11.16627
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