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Interaction Between ITM2B and GLUT9 Links Urate Transport to Neurodegenerative Disorders

Hyperuricemia plays a critical causative role in gout. In contrast, hyperuricemia has a protective effect in neurodegenerative disorders, including Alzheimer’s Disease. Genetic variation in the SLC2A9 gene, encoding the urate transporter GLUT9, exerts the largest single-gene effect on serum uric aci...

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Bibliografiske detaljer
Udgivet i:Front Physiol
Main Authors: Mandal, Asim K., Mount, David B.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818471/
https://ncbi.nlm.nih.gov/pubmed/31695625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01323
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