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Crowder-Induced Conformational Ensemble Shift in Escherichia coli Prolyl-tRNA Synthetase

The effect of molecular crowding on the structure and function of Escherichia coli prolyl-transfer RNA synthetase (Ec ProRS), a member of the aminoacyl-transfer RNA synthetase family, has been investigated using a combined experimental and theoretical method. Ec ProRS is a multidomain enzyme; couple...

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Publicat a:Biophys J
Autors principals: Adams, Lauren M., Andrews, Ryan J., Hu, Quin H., Schmit, Heidi L., Hati, Sanchita, Bhattacharyya, Sudeep
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818166/
https://ncbi.nlm.nih.gov/pubmed/31542226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.08.033
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