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Coordinated roles for glycans in regulating the inhibitory function of CD22 on B cells

CD22 is an inhibitory B cell co-receptor that recognizes sialic acid-containing glycoconjugates as ligands. Interactions with its glycan ligands are key to regulating the ability of CD22 to modulate B cell function, the most widely explored of which is antagonizing B cell receptor (BCR) signaling. M...

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Detalles Bibliográficos
Publicado en:Biomed J
Main Authors: Enterina, Jhon R., Jung, Jaesoo, Macauley, Matthew S.
Formato: Artigo
Idioma:Inglês
Publicado: Chang Gung University 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818156/
https://ncbi.nlm.nih.gov/pubmed/31627864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bj.2019.07.010
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