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Coordinated roles for glycans in regulating the inhibitory function of CD22 on B cells

CD22 is an inhibitory B cell co-receptor that recognizes sialic acid-containing glycoconjugates as ligands. Interactions with its glycan ligands are key to regulating the ability of CD22 to modulate B cell function, the most widely explored of which is antagonizing B cell receptor (BCR) signaling. M...

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Détails bibliographiques
Publié dans:Biomed J
Auteurs principaux: Enterina, Jhon R., Jung, Jaesoo, Macauley, Matthew S.
Format: Artigo
Langue:Inglês
Publié: Chang Gung University 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6818156/
https://ncbi.nlm.nih.gov/pubmed/31627864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bj.2019.07.010
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