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Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species

Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries, and is characterized by slow retinal degeneration linked to chronic reactive oxygen species (ROS) in the retinal pigmented epithelium (RPE). The molecular mechanisms leading to RPE dysfunction in respons...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Meyer, Jesse G., Garcia, Thelma Y., Schilling, Birgit, Gibson, Bradford W., Lamba, Deepak A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817852/
https://ncbi.nlm.nih.gov/pubmed/31659173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51777-7
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