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cis Elements that Mediate RNA Polymerase II Pausing Regulate Human Gene Expression
Aberrant gene expression underlies many human diseases. RNA polymerase II (Pol II) pausing is a key regulatory step in transcription. Here, we mapped the locations of RNA Pol II in normal human cells and found that RNA Pol II pauses in a consistent manner across individuals and cell types. At more t...
Enregistré dans:
| Publié dans: | Am J Hum Genet |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6817524/ https://ncbi.nlm.nih.gov/pubmed/31495490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.08.003 |
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