Hyperpolarized in vivo pH imaging reveals grade-dependent acidification in prostate cancer

There is an unmet clinical need for new and robust imaging biomarkers to distinguish indolent from aggressive prostate cancer. Hallmarks of aggressive tumors such as a decrease in extracellular pH (pH(e)) can potentially be used to identify aggressive phenotypes. In this study, we employ an optimize...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Korenchan, David E., Bok, Robert, Sriram, Renuka, Liu, Kristina, Santos, Romelyn Delos, Qin, Hecong, Lobach, Iryna, Korn, Natalie, Wilson, David M., Kurhanewicz, John, Flavell, Robert R.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6817439/
https://ncbi.nlm.nih.gov/pubmed/31692908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27225
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