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Two novel CPS1 mutations in a case of carbamoyl phosphate synthetase 1 deficiency causing hyperammonemia and leukodystrophy

BACKGROUND: Carbamoyl phosphate synthetase 1 deficiency (CPS1D) is a rare autosomal recessive disorder of the urea cycle, mostly characterized by hyperammonemia and the concomitant leukodystrophy. The onset of CPS1D can be at any age, and the clinical manifestations are variable and atypical. Geneti...

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Foilsithe in:J Clin Lab Anal
Main Authors: Chen, Xihui, Yuan, Lijuan, Sun, Mao, Liu, Qingbo, Wu, Yuanming
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816849/
https://ncbi.nlm.nih.gov/pubmed/29314318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.22375
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