Influence of Biotechnological Processes, Speed of Formulation Flow and Cellular Concurrent Stream-Integration on Insulin Production from β-cells as a Result of Co-Encapsulation with a Highly Lipophilic Bile Acid

INTRODUCTION: We have shown that incorporation of the hydrophilic bile acid, ursodeoxycholic acid, into β-cell microcapsules exerted positive effects on microcapsules’ morphology and size, but these effects were excipient and method dependent. Cell viability remained low which suggests low octane-wa...

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Veröffentlicht in:Cell Mol Bioeng
Hauptverfasser: Mooranian, Armin, Negrulj, Rebecca, Takechi, Ryu, Jamieson, Emma, Morahan, Grant, Al-Salami, Hani
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816685/
https://ncbi.nlm.nih.gov/pubmed/31719879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-017-0510-y
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