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Extracellular Matrix Stiffening Induces a Malignant Phenotypic Transition in Breast Epithelial Cells

Tumors are much stiffer than healthy tissue, and progressively stiffen as the cancer develops. Tumor stiffening is largely the result of extracellular matrix (ECM) remodeling, for example, deposition and crosslinking of collagen I. Well established in vitro models have demonstrated the influence of...

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Bibliografske podrobnosti
izdano v:Cell Mol Bioeng
Main Authors: Stowers, Ryan S., Allen, Shane C., Sanchez, Karla, Davis, Courtney L., Ebelt, Nancy D., Van Den Berg, Carla, Suggs, Laura J.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816676/
https://ncbi.nlm.nih.gov/pubmed/31719853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-016-0468-1
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