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Extracellular Matrix Stiffening Induces a Malignant Phenotypic Transition in Breast Epithelial Cells

Tumors are much stiffer than healthy tissue, and progressively stiffen as the cancer develops. Tumor stiffening is largely the result of extracellular matrix (ECM) remodeling, for example, deposition and crosslinking of collagen I. Well established in vitro models have demonstrated the influence of...

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Detalhes bibliográficos
Publicado no:Cell Mol Bioeng
Main Authors: Stowers, Ryan S., Allen, Shane C., Sanchez, Karla, Davis, Courtney L., Ebelt, Nancy D., Van Den Berg, Carla, Suggs, Laura J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6816676/
https://ncbi.nlm.nih.gov/pubmed/31719853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-016-0468-1
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