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Computational design and interpretation of single-RNA translation experiments
Advances in fluorescence microscopy have introduced new assays to quantify live-cell translation dynamics at single-RNA resolution. We introduce a detailed, yet efficient sequence-based stochastic model that generates realistic synthetic data for several such assays, including Fluorescence Correlati...
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| Udgivet i: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6816579/ https://ncbi.nlm.nih.gov/pubmed/31618265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007425 |
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